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J Affect Disord. 2000 Jan-Mar;57(1-3):49-54.

The course of depression in elderly subjects with and without dementia.

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1
Department of Psychiatry, University Hospital Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

Abstract

BACKGROUND:

A persistent course of depression has been described in subjects with and without dementia. Up to the present it is unclear to what extent dementia affects the prognosis of depression.

METHOD:

At baseline and at 6 and 12 months follow-up AGECAT depression diagnoses were made in 49 subjects with and 72 subjects without DSM-III-R dementia living in homes for the elderly.

RESULTS:

Adjusting for demographic characteristics and physical health, dementia was not associated with the severity of depression at follow up. The baseline depression severity and to a lesser extent somatic complaints predicted a bad prognosis of depression in the total sample.

LIMITATIONS:

Because of the high vulnerability of the residents the results cannot be generalised to other populations of elderly subjects.

CONCLUSION:

Depression is persistent in residents of homes for the elderly. Dementia does not affect its course.

PMID:
10708815
[Indexed for MEDLINE]
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