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AJR Am J Roentgenol. 2000 Mar;174(3):769-74.

Prognostic value of thoracic FDG PET imaging after treatment for non-small cell lung cancer.

Author information

1
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.

Abstract

OBJECTIVE:

We determined the prognostic value of 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) for patients with treated lung cancer.

MATERIALS AND METHODS:

We examined patients who underwent FDG PET after first-line treatment for non-small cell lung cancer. FDG PET results were correlated with survival rates to determine whether FDG PET findings were predictive of outcomes.

RESULTS:

After initial therapy, 113 patients with non-small cell lung cancer underwent FDG PET. One hundred patients had positive FDG PET results and a median survival of 12 months (95% confidence interval, 9.2-15.4). Thirteen patients had negative FDG PET results, and 11 (85%) of these patients are still living at a median follow-up of 34 months. The difference in survival for patients with positive and negative FDG PET results was statistically significant (p = 0.002).

CONCLUSION:

FDG PET has prognostic value and strongly correlates with survival rates of patients with treated lung cancer. Patients with positive FDG PET results have a significantly worse prognosis than patients with negative results. Additionally, FDG PET may be helpful in guiding therapeutic treatments.

PMID:
10701623
DOI:
10.2214/ajr.174.3.1740769
[Indexed for MEDLINE]

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