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Otolaryngol Head Neck Surg. 2000 Mar;122(3):340-5.

Endolymphatic mastoid shunt: a reevaluation of efficacy.

Author information

1
Departments of Otolaryngology and Statistics, Ohio State University, OH, USA.

Abstract

OBJECTIVES:

The main goal of this paper was to statistically reevaluate the efficacy of the endolymphatic shunt procedure for Meniere's disease.

METHODS:

Thomsen et al (Arch Otolaryngol 1981;107:271-7) reported on the placebo effect in surgery for Meniere's disease in a controlled double-blind study. Thirty patients with typical Meniere's disease in whom medical treatment failed participated in the study. A placebo-controlled blinded surgical study has not since been replicated. We performed a retrospective statistical analysis using data extracted from the published report and reanalyzed it using both the original and new statistical measures and techniques.

RESULTS:

The original conclusions drawn by Thomsen et al differed considerably from ours in 5 key areas, including postoperative vertigo, nausea and vomiting, tinnitus, and combined score.

CONCLUSIONS:

This analysis strongly supports the effectiveness of the endolymphatic shunt in the management of Meniere's disease and refutes the placebo effect previously proposed.

PMID:
10699806
DOI:
10.1067/mhn.2000.101575
[Indexed for MEDLINE]

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