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Am J Psychiatry. 2000 Mar;157(3):466-8.

Comorbidity of attention deficit hyperactivity disorder with early- and late-onset bipolar disorder.

Author information

  • 1Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, MA 02114, USA. sachsg@aol.com

Abstract

OBJECTIVE:

The relationship between attention deficit hyperactivity disorder (ADHD) and earlier age at onset of affective illness was examined in probands with a history of bipolar disorder.

METHOD:

The authors assessed 56 adult bipolar subjects. Those with a history of childhood ADHD (N=8) were age and sex matched with bipolar subjects without a history of childhood ADHD (N=8).

RESULTS:

The age at onset of the first affective episode was lower for the subjects with bipolar disorder and a history of childhood ADHD (mean=12.1 years, SD=4.6) than for those without a history of childhood ADHD (mean=20. 0 years, SD=11.3).

CONCLUSIONS:

ADHD in children of bipolar probands might identify children at highest risk for development of bipolar disorder.

PMID:
10698829
DOI:
10.1176/appi.ajp.157.3.466
[PubMed - indexed for MEDLINE]
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