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Gastroenterol Clin North Am. 1999 Dec;28(4):809-30, v.

Diagnostic evaluation in gastroesophageal reflux disease.

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Department of Gastroenterology, Johns Hopkins Bayview Medical Center, Baltimore, Maryland, USA.


Gastroesophageal reflux disease (GERD) describes the clinical manifestations of reflux of gastric contents and the associated symptoms and patterns of tissue injury. Although its exact prevalence is difficult to determine, there is no doubt the GERD is the most common esophageal disease and probably among the most prevalent conditions seen in the primary care setting. GERD has a wide clinical spectrum, making the diagnostic evaluation challenging and complicated at times. Confirmatory test are rarely needed in patients with typical symptoms of heartburn or regurgitation who have a good clinical response to GERD therapy. This article describes the diagnostic tests necessary for some cases of GERD.

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