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Zh Vyssh Nerv Deiat Im I P Pavlova. 1999 Nov-Dec;49(6):1052-6.

[The effect of scopolamine on the spatial organization of rat cortical potentials].

[Article in Russian]

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Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.


The influence of scopolamine (1 mg/kg, i.p.) on the spatial organization of the neocortical electrical activity was studied in rats. A decrease in the spectral power and coherence of brain potentials in the range of the dominant theta-rhythm peak (6.00-7.25 Hz) and their increase in the adjacent low-frequency band were observed. Both indices were decreased in the wide beta band (19.00-30.00 Hz). The described changes took place over the whole areas of the right hemisphere and parieto-temporal region of the left hemisphere. The obtained results are discussed with respect to the role of the cholinergic brain system in the higher nervous activity.

[Indexed for MEDLINE]

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