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Antimicrob Agents Chemother. 2000 Mar;44(3):771-2.

Pulsed ultrasound enhances the killing of Escherichia coli biofilms by aminoglycoside antibiotics in vivo.

Author information

1
Department of Microbiology, Brigham Young University, Provo, Utah.

Abstract

Escherichia coli biofilms on two polyethylene disks were implanted subcutaneously into rabbits receiving systemic gentamicin. Ultrasound was applied for 24 h to one disk. Both disks were removed, and viable bacteria were counted. Pulsed ultrasound significantly reduced bacterial viability below that of nontreated biofilms without damage to the skin.

PMID:
10681355
PMCID:
PMC89763
[Indexed for MEDLINE]
Free PMC Article

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