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Curr Opin Microbiol. 2000 Feb;3(1):65-72.

Bacterial pili: molecular mechanisms of pathogenesis.

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Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, MO 63110, USA.


Gram-negative bacteria produce a diverse array of pili that mediate microbe-microbe and host-pathogen interactions important in the development of disease. The structural and functional characterization of these organelles, particularly their role in triggering signals in both the bacterium and the host upon attachment, has begun to reveal the molecular mechanisms of bacterial diseases.

[Indexed for MEDLINE]

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