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Curr Opin Microbiol. 2000 Feb;3(1):29-34.

Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis.

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Department of Genetics, Department of Molecular Biology, Wellman 10, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.


In the past year, a Caenorhabditis elegans-Pseudomonas aeruginosa pathogenesis model has been developed to facilitate the systematic dissection of both host and pathogen genes involved in pathogenic interactions. Analysis of the P. aeruginosa-C. elegans interaction should shed light on the larger question of how organisms interact at the molecular level in antagonistic relationships.

[Indexed for MEDLINE]

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