Format

Send to

Choose Destination
Curr Opin Genet Dev. 2000 Feb;10(1):65-9.

Controlling the end of the cell cycle.

Author information

1
Wellcome Trust Genome Campus, The Sanger Centre, Hinxton, CB10 1SA, UK. lmc@sanger.ac.uk.

Abstract

The past year has seen significant advances in our understanding of how the events which occur at the end of mitosis, such as cytokinesis and the inactivation of mitotic cyclin dependent kinases are triggered, and also how they are prevented from occurring prematurely or inappropriately. This control is achieved through a combination of temporally ordered proteolytic events and changes in the subcellular localisation of proteins. These studies have also revealed that the nucleolus and spindle pole bodies play a key role in this regulation.

PMID:
10679389
DOI:
10.1016/s0959-437x(99)00044-1
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center