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Curr Opin Cell Biol. 2000 Feb;12(1):35-41.

Kinesins and microtubules: their structures and motor mechanisms.

Author information

1
Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143, USA. sablin@msg.ucsf.edu

Abstract

Atomic resolution three-dimensional structures of two oppositely directed kinesin motors - conventional kinesin and non-claret disjunctional (ncd) protein - are now available in their functional dimeric form. A detailed model of the microtubule has also been recently obtained by docking the 3.7 A structure of tubulin into a 20 A map of the microtubule. Recent structural studies of kinesin motors and their microtubule tracks are contributing to our current understanding of kinesin motor mechanisms.

PMID:
10679355
DOI:
10.1016/s0955-0674(99)00054-x
[Indexed for MEDLINE]

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