Abstract
Pyridoxal-5'-phosphate (vitamin B6) binding enzymes form a large superfamily that contains at least five different folds. The availability of an increasing number of known three-dimensional structures for members of this superfamily has allowed a detailed structural classification. Most progress has been made with the fold type I or aspartate aminotransferase family.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Alanine Racemase / chemistry
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Alanine Racemase / metabolism
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Alanine Transaminase / chemistry
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Alanine Transaminase / metabolism
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Animals
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Aspartate Aminotransferases / chemistry
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Aspartate Aminotransferases / metabolism
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D-Alanine Transaminase
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Enzymes / chemistry*
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Enzymes / metabolism*
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Humans
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Phosphorylases / chemistry
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Phosphorylases / metabolism
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Protein Folding
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Protein Structure, Secondary
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Protein Structure, Tertiary
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Pyridoxine / metabolism*
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Tryptophan Synthase / chemistry
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Tryptophan Synthase / metabolism
Substances
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Enzymes
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Phosphorylases
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Aspartate Aminotransferases
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Alanine Transaminase
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D-Alanine Transaminase
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Tryptophan Synthase
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Alanine Racemase
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Pyridoxine