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Clin Exp Dermatol. 2000 Jan;25(1):55-6.

Subcutaneous sarcoidosis associated with vitiligo, pernicious anaemia and autoimmune thyroiditis.

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Department of Dermatology; Respiratory Medicine, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.


We report a patient with pernicious anaemia, primary autoimmune hypothyroidism and vitiligo, who presented with subcutaneous nodules. Histopathology of the nodules revealed noncaseating granulomas, consistent with a diagnosis of sarcoidosis. Mild pulmonary sarcoid was also detected. Although an association between sarcoidosis and other autoimmune diseases is well-recognized, the presence of the particular autoimmune diseases in our patient and the involvement of subcutaneous fat in the sarcoidal inflammation, appears to represent a most unusual clinicopathological combination.

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