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Nat Cell Biol. 2000 Feb;2(2):E23-5.

CD95: more than just a death factor?

Erratum in

  • Nat Cell Biol 2000 Mar;2(3):E50.

Abstract

The CD95 protein delivers crucial signals for lymphocyte death, and may also negatively regulate T-lymphocyte activation by preventing the influx of calcium ions from the cell's exterior. The block in calcium-ion influx occurs through the activation of acidic sphingomyelinase and the release of ceramide, a metabolite that can also induce cell death.

PMID:
10655597
DOI:
10.1038/35000092
[Indexed for MEDLINE]

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