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Ophthalmology. 2000 Jan;107(1):68-71.

A randomized controlled trial of intracameral lidocaine during phacoemulsification under topical anesthesia.

Author information

1
Department of Ophthalmology, Royal United Hospital, Bath, United Kingdom.

Abstract

OBJECTIVE:

To test the hypothesis that adjunctive intracameral 1% lidocaine reduces intraoperative pain during phacoemulsification using topical anesthesia.

DESIGN:

Prospective, double-masked, randomized, controlled trial.

PARTICIPANTS:

A total of 200 patients undergoing routine phacoemulsification under topical 1% tetracaine were studied.

INTERVENTION:

Randomization to 0.5 ml intracameral, unpreserved, epinephrine-free 1% lidocaine or placebo was conducted.

MAIN OUTCOME MEASURE:

Intraoperative pain was quantified by the patients using a 0-10 visual analog pain scale.

RESULTS:

Intraoperative pain scores (+/- standard deviation) for the lidocaine and control groups were 1.29 +/-1.24 and 1.44 +/- 1.33, respectively (P > 0.35).

CONCLUSIONS:

In a rigorously double-masked, prospective, randomized, controlled trial there was no significant reduction in intraoperative pain when intracameral 1% lidocaine was used during phacoemulsification under topical anesthesia.

Comment in

PMID:
10647721
[Indexed for MEDLINE]

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