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Pharmacotherapy. 2000 Jan;20(1):13-22.

HIV-associated lipodystrophy syndrome.

Author information

1
Department of Pharmacy, University of North Carolina Hospitals and Clinics, Chapel Hill, USA.

Abstract

Highly active antiretroviral therapy (HAART) for human immunodeficiency virus-1 (HIV-1) and prophylactic therapy for opportunistic infections have increased survival. Adverse effects of HAART include lipid profile alterations, diabetes mellitus, and fat redistribution. These metabolic and physical changes are called the HIV-associated lipodystrophy syndrome. A link to protease inhibitors has been suggested, and more recently to nucleoside reverse transcriptase inhibitors and factors related to duration of HIV-1 infection itself.

PMID:
10641972
DOI:
10.1592/phco.20.1.13.34667
[Indexed for MEDLINE]

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