Format

Send to

Choose Destination
Free Radic Res. 1999 Dec;31(6):671-9.

Role of nitric oxide in cancer biology.

Author information

1
Applied Physiology Branch, Defence Medical Research Institute, National University of Singapore, Singapore. nmiv19@nus.edu.sg

Abstract

The role of nitric oxide (NO) in tumorigenesis is multifactorial. NO can participate in the complicated process of carcinogenesis by mediating DNA damage in early phases of tumorigenesis, as well as support tumor progression through the induction of angiogenesis and suppression of the immune response. This paper addresses the effects of NO on transcriptional regulation following DNA damage and cyclooxygenase expression in the multistep process of tumorigenesis.

PMID:
10630689
DOI:
10.1080/10715769900301231a
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center