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Hematol Oncol Clin North Am. 1999 Dec;13(6):1127-43.

The role of adhesion receptors in the pathogenesis of multiple myeloma.

Author information

1
Division of Hematology and Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA. witzig@mayo.edu

Abstract

There is now an improved understanding of the types of adhesion receptors present on normal and malignant plasma cells. This knowledge has been helpful in identifying plasma cells and in beginning to understand the pathogenesis of myeloma. Future research is needed to delineate the signaling pathways used by the plasma cell after the adhesion receptor binds to its ligands. This information should help in designing more effective therapy for this fatal disease.

PMID:
10626140
DOI:
10.1016/s0889-8588(05)70116-7
[Indexed for MEDLINE]

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