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Br J Anaesth. 1999 Aug;83(2):302-20.

Magnesium: physiology and pharmacology.

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Department of Anaesthesia, Royal Surrey County Hospital, Guildford, Surrey, UK.


Magnesium has an established role in obstetrics and an evolving role in other clinical areas, in particular cardiology. Many of the effects involving magnesium are still a matter of controversy. Over the next decade, it is likely that improvements in the measurement of magnesium, a clearer understanding of the mechanisms of its actions and further results of clinical studies will help to elucidate its role, both in terms of treating deficiency and as a pharmacological agent.

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