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J Ethnopharmacol. 1999 Nov 30;67(3):361-5.

Antitussive effect of Adhatoda vasica extract on mechanical or chemical stimulation-induced coughing in animals.

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Department of Pharmacology and Toxicology, Hindustan Antibiotics Ltd., Pimpri, Pune, India.


The antitussive activity of Adhatoda vasica (AV) extract was evaluated in anaesthetized guinea pigs and rabbits and in unanaesthetized guinea pigs. AV was shown to have a good antitussive activity. Intravenously, it was 1/20-1/40 as active as codeine on mechanically and electrically induced coughing in rabbits and guinea-pigs. After oral administration to the guinea-pig the antitussive activity of AV was similar to codeine against coughing induced by irritant aerosols.

[Indexed for MEDLINE]

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