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J Ethnopharmacol. 1999 Nov 30;67(3):253-8.

Post-coital antifertility activity of Acalypha indica L.

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1
Department of Chemistry, Gulbarga University, India.

Abstract

Four successive solvent extracts of the whole plant Acalypha indica L. (Euphorbiaceae) were tested for post-coital antifertility activity in female albino rats. Of these, the petroleum ether and ethanol extracts were found to be most effective in causing significant anti-implantation activity. The antifertility activity was reversible on withdrawal of the treatment of the extracts. Both the extracts at 600 mg/kg body weight showed estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity.

PMID:
10617059
[Indexed for MEDLINE]
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