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Curr Opin Neurobiol. 1999 Dec;9(6):772-7.

Effects of Conus peptides on the behavior of mice.

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Department of Biology, University of Utah, Salt Lake City 84112-0840, USA.


When different cone snail peptides are injected into the CNS of vertebrates, they elicit diverse behaviors primarily because of their selectivity for specific receptor or ion channel subtypes. The subcellular context of the highly localized targets (i.e. the presence of other cellular elements that are functionally linked to the targets of conopeptides) is another determinant of the elicited behavior. Recent studies have advanced our understanding of the mechanisms by which four conopeptides produce different behaviors in mice.

[Indexed for MEDLINE]

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