Format

Send to

Choose Destination
See comment in PubMed Commons below
J Sleep Res. 1993 Jun;2(2):63-69.

A neuronal group theory of sleep function.

Author information

1
Department of Physiology & Biophysics, University of Tennessee, Memphis, TN, USA.

Abstract

A new theory of sleep function is presented within the context of the neuronal group selection hypothesis, which emphasizes that neuronal groups compete for neurons via use-dependent synaptic formation and atrophy. It is hypothesized that sleep serves to stabilize these competitive processes by providing a pattern of stimulation that serves to maintain a synaptic infrastructure upon which wakefulness-driven synaptic changes are superimposed. Sleep is 'quantal' in nature in that sleep is a statistical property of a population of neuronal groups in different states. The theory unifies past theories of sleep function yet simultaneously provides a fundamental new paradigm for sleep research.

PMID:
10607073
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center