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Trends Microbiol. 1999 Dec;7(12):500-5.

Pipes and wiring: the regulation of copper uptake and distribution in yeast.

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Dept of Biological Chemistry, University of Michigan Medical School, Ann Arbor, MI 48109-0606, USA.


Copper is required for processes as conserved as respiration and as specialized as protein modification. Recent exciting findings from studies in yeast cells have revealed the presence of specific pathways for copper transport, trafficking and signal transduction that maintain the delicate balance of this essential yet toxic metal ion.

[Indexed for MEDLINE]

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