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Trends Microbiol. 1999 Dec;7(12):488-93.

Mutation as an origin of genetic variability in Helicobacter pylori.

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Dept of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada T6G 2H7.


The availability of two complete Helicobacter pylori genome sequences and recent studies of its population genetics have provided a detailed picture of genetic diversity in this important human gastric pathogen. It is believed that, in addition to genetic recombination, de novo mutation could have a role in generating the high level of genetic variation in H. pylori.

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[Indexed for MEDLINE]

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