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Curr Opin Biotechnol. 1999 Dec;10(6):528-35.

Current biology of VEGF-B and VEGF-C.

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Ludwig Institute for Cancer Research, Box 240, Stockholm, SE-171 77, Sweden.


Endothelial growth factors and their receptors may provide important therapeutic tools for the treatment of pathological conditions characterised by defective or aberrant angiogenesis. Vascular endothelial growth factor (VEGF) is pivotal for vasculogenesis and for angiogenesis in normal and pathological conditions. VEGF-B and VEGF-C provide this gene family with additional functions, for example, VEGF-C also regulates lymphangiogenesis.

[Indexed for MEDLINE]

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