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Gynecol Oncol. 1999 Dec;75(3):345-8.

Utility of the monoclonal antibody HIK1083 in the diagnosis of adenoma malignum of the uterine cervix.

Author information

1
Cancer Institute Hospital, Department of Pathology, Cancer Institute, 1-37-1, Kami-Ikebukuro, Toshima-ku, Tokyo, 170-8455, Japan.

Abstract

OBJECTIVES:

The aim of this study was to qualify a staining technique for the diagnosis of adenoma malignum.

METHODS:

The gastric mucin expression of adenoma malignum, ordinary endocervical adenocarcinoma, and normal cervical glands was immunohistochemically compared using the monoclonal antibody HIK1083.

RESULTS:

The three categories were clearly distinguished, with 90% (9/10) of cases with positive adenoma malignum, 30% (3/10) of cases with weakly positive ordinary cervical adenocarcinoma, and no (0/10) cases of positive normal cervical glands.

CONCLUSIONS:

This preliminary report indicates that the use of HIK1083 is valuable in the diagnosis of adenoma malignum.

PMID:
10600287
DOI:
10.1006/gyno.1999.5622
[Indexed for MEDLINE]

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