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Curr Opin Neurol. 1999 Oct;12(5):565-71.

Chemotherapeutic neuropathy.

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1
Mayo Medical Center, Rochester, MN 55905, USA. windebank.anthony@mayo.edu

Abstract

Peripheral neurotoxicity is a dose-limiting side-effect for a number of effective chemotherapeutic agents, including platinum compounds, taxanes, and vinca alkaloids. New experimental chemotherapy drugs that cause neuropathy include suramin and Dolostatin-10. A better understanding of cellular mechanisms will lead to novel treatment strategies that will protect neurons without decreasing therapeutic efficacy.

PMID:
10590893
[Indexed for MEDLINE]
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