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Clin Exp Rheumatol. 1999 Nov-Dec;17(6 Suppl 18):S66-8.

Methotrexate and leflunomide combination therapy for patients with active rheumatoid arthritis.

Author information

1
Division of Rheumatology, Albany Medical College, New York 12208-3479, USA.

Abstract

An open-label, one-year study was conducted to evaluate the safety and clinical response to leflunomide and methotrexate combination therapy for rheumatoid arthritis. Study results revealed tolerable safety, no significant pharmacokinetic interactions between methotrexate and leflunomide, and suggested improved clinical response with combination therapy.

PMID:
10589360
[Indexed for MEDLINE]

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