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J Pediatr. 1999 Dec;135(6):768-9.

Failure of pre-diarrheal antibiotics to prevent hemolytic uremic syndrome in serologically proven Escherichia coli O157:H7 gastrointestinal infection.

Author information

1
Department of Pediatrics, The University of Tokyo, Mejirodai Campus, Mejirodai, Bunkyo-ku, Tokyo, Japan.

Abstract

A girl had hemolytic uremic syndrome after Escherichia coli O157:H7 infection, despite pre-diarrheal administration of an antibiotic that prevented detectable intestinal colonization. This report casts doubt on the advisability of antibiotic therapy for E coli O157:H7 infections and has implications for our understanding of the mechanism of this disorder.

PMID:
10586184
DOI:
10.1016/s0022-3476(99)70100-9
[Indexed for MEDLINE]

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