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Bioorg Med Chem Lett. 1999 Nov 15;9(22):3217-20.

Unsymmetrical cyclic ureas as HIV-1 protease inhibitors: novel biaryl indazoles as P2/P2' substituents.

Author information

1
DuPont Pharmaceuticals Company, Experimental Station, Wilmington, DE 19880-0500, USA.

Abstract

The preparation of unsymmetrical cyclic ureas bearing novel biaryl indazoles as P2/P2' substituents was undertaken, utilizing a Suzuki coupling reaction as the key step. Compound 6i was equipotent to the lead compound of the series SE063.

PMID:
10576691
DOI:
10.1016/s0960-894x(99)00564-8
[Indexed for MEDLINE]

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