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Magn Reson Med. 1999 Dec;42(6):1033-8.

Quantitative assessment of pulmonary perfusion with dynamic contrast-enhanced MRI.

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1
Department of Radiology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, MA 02215, USA. hhatabu@caregroup.harvard.edu

Abstract

The feasibility of qualitative assessment of pulmonary perfusion using dynamic contrast enhanced MRI with ultra-short TE has recently been demonstrated. In the current study, quantitative analysis was attempted based on the indicator dilution principle using a pig model of pulmonary embolism. The results were compared with the absolute pulmonary perfusion obtained with colored microspheres. The inverse of apparent mean transit time (1/tau(app)), distribution volume (V), and V/tau(app) were correlated well with the absolute lung perfusion. This study demonstrates that MR has the potential to evaluate pulmonary perfusion quantitatively. Magn Reson Med 42:1033-1038, 1999.

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