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Rhinology. 1999 Sep;37(3):122-4.

McCune-Albright syndrome with fibrous dysplasia of the paranasal sinuses.

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Department of Otorhinolaryngology, Trakya University, Faculty of Medicine, Edirne, Turkey.


We report a 19-year old female patient with the McCune-Albright syndrome, which is a rare disease consisting of polyostotic fibrous dysplasia (FD) of bone associated with brown pigmented areas of the skin and several endocrine dysfunctions. The patient had FD involving the paranasal sinuses, the middle turbinate and the skull. The endocrine dysfunction of the patient concerns both growth hormone and prolactin hypersecretion. Because the patient had no major symptoms, neither surgical nor medical treatment was applied. Five-year follow-up revealed no complication and enlargement of the lesion.

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