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Eur J Radiol. 1999 Sep;31(3):165-9.

Diffusion-weighted MR imaging in multiple sclerosis: comparison with contrast-enhanced study.

Author information

1
Department of Radiology, Kyorin University School of Medicine, Mitaka, Tokyo, Japan. rxl03761@nifty.ne.jp

Abstract

OBJECTIVE:

To assess the utility of cerebral diffusion-weighted MR imaging in the diagnosis of multiple sclerosis (MS) in comparison with contrast-enhanced T1-weighted imaging.

METHODS AND MATERIALS:

We reviewed T2-weighted spin-echo (SE), fluid-attenuated inversion-recovery (FLAIR), contrast-enhanced T1-weighted SE and echo-planar diffusion-weighted images (DWIs) obtained in seven patients with definite MS on nine occasions.

RESULTS:

In total, 94 plaques were demonstrated on T2-weighted SE and/or FLAIR images. A total of 13 of these plaques showed enhancement on contrast-enhanced T1-weighted images and hyperintensity on DWIs, and five non-enhancing plaques showed hyperintensity on DWIs.

CONCLUSION:

Diffusion-weighted imaging, which provides information based on pathophysiology different from contrast-enhanced imaging, is a potential supplementary technique for characterizing MS plaques.

PMID:
10566514
DOI:
10.1016/s0720-048x(98)00131-4
[Indexed for MEDLINE]

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