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Arch Biochem Biophys. 1999 Dec 1;372(1):166-72.

Host cell signal transduction during Listeria monocytogenes infection.

Author information

1
Theodor-Boveri-Institut für Biowissenschaften der Universität Würzburg, Lehrstuhl für Mikrobiologie, Am Hubland, Würzburg, 97074, Germany. kuhn@biozentrum.uni-wuerzburg.de

Abstract

The facultative intracellular bacterial pathogen Listeria monocytogenes invades and multiplies in many mammalian cell types. During the interaction with its host cells it strongly interferes with and modulates host cell functions. In the present review we summarize the current knowledge on the modulation of signal transduction pathways by secreted listerial products prior to bacterium-cell contact, during uptake, or while L. monocytogenes resides in the different intracellular compartments.

PMID:
10562430
DOI:
10.1006/abbi.1999.1487
[Indexed for MEDLINE]

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