Format

Send to

Choose Destination
See comment in PubMed Commons below
J Clin Pathol. 1999 May;52(5):388-9.

Eosinophilic myelodysplasia transforming to acute lymphoblastic leukaemia.

Author information

1
Department of Haematology, Bradford Royal Infirmary, UK.

Abstract

A 43 year old male presented with a marked eosinophilia and associated systemic symptoms. A diagnosis of myelodysplasia was made on the basis of bone marrow morphology and karyotype. Over a 12 month period the disease transformed into acute lymphoblastic leukaemia, confirmed by flow cytometry, cytochemistry, and immunohistochemistry. Karyotyping was abnormal with 5q- and -7 which persisted from diagnosis through to blastic transformation. He died following initial induction chemotherapy. Eosinophilic myelodysplasia is an uncommon condition in haematological practice and no previous report of lymphoblastic transformation has been found.

PMID:
10560363
PMCID:
PMC1023079
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center