Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Cell Biol. 1999 Jun;1(2):E47-53.

Regulation of the APC and the exit from mitosis.

Author information

1
Department of Physiology, University of California, San Francisco 94143-0444, USA. dmorgan@cgl.ucsf.edu

Abstract

The events of late mitosis, from sister-chromatid separation to cytokinesis, are governed by the anaphase-promoting complex (APC), a multisubunit assembly that triggers the ubiquitin-dependent proteloysis of key regulatory proteins. An intricate regulatory network governs APC activity and helps to ensure that late mitotic events are properly timed and coordinated.

PMID:
10559897
DOI:
10.1038/10039
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Support Center