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Med Klin (Munich). 1999 Oct 15;94 Suppl 3:58-61.

[Molecular biology studies of a multicenter phase III study (SIC Study)].

[Article in German]

Author information

  • 1Klinik und Poliklinik für Viszeral-, Thorax- und Gefässchirurgie, Universitätsklinikums, TU Dresden.


Transcription factors adjust the up- and downregulation of inflammatory genes. Within the bounds of the SIC-study (Selenium in Intensive Care) the authors will investigate the role of transcription factors NF-kappa B and AP-1 in S.I.R.S/septic patients. The goal of these investigations is the corroboration of therapy of septic patients with sodium selenite at the molecular biological level.

[PubMed - indexed for MEDLINE]
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