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J Agric Food Chem. 1999 Jul;47(7):2666-70.

Determination of stilbenes (trans-astringin, cis- and trans-piceid, and cis- and trans-resveratrol) in Portuguese wines.

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Faculté des Sciences Pharmaceutiques, Centre de Formation et de Recherche en OEnologie, Université de Montpellier I, Avenue Charles Flahault, 34060 Montpellier Cedex 2, France.


Stilbenes have been shown to have cancer chemopreventive activity and to protect lipoproteins from oxidative damage. A method is described for their direct determination in different types of wine using high-performance liquid chromatography with ultraviolet detection. In a survey of 120 commercial wines from Portugal and France, the highest concentrations of stilbenes were found in red wines. The glucosides of resveratrol were present in higher concentrations than the free isomers. Isolation from wine and characterization of trans-astringin in a large quantity are described for the first time.

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