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Phytother Res. 1999 Nov;13(7):571-4.

Neuroprotective role of curcumin from curcuma longa on ethanol-induced brain damage.

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Department of Biochemistry, Annamalai University, Annamalai Nagar-608 002, India.


In the present study, curcumin from Curcuma longa was screened for neuroprotective activity using ethanol as a model of brain injury. Oral administration of curcumin to rats caused a significant reversal in lipid peroxidation, brain lipids and produced enhancement of glutathione, a non-enzymic antioxidant in ethanol intoxicated rats, revealing that the antioxidative and hypolipidaemic action of curcumin is-responsible for its protective role against ethanol induced brain injury.

[Indexed for MEDLINE]

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