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Trends Biochem Sci. 1999 Nov;24(11):428-32.

How membrane proteins travel across the mitochondrial intermembrane space.

Author information

1
Dept of Biochemistry, Biozentrum, University of Basel, CH-4056 Basel, Switzerland.

Abstract

A newly discovered family of small proteins in the yeast mitochondrial intermembrane space mediates import of hydrophobic proteins from the cytoplasm into the inner membrane. Loss of one of these chaperone-like proteins from human mitochondria results in a disease that causes deafness, muscle weakness and blindness.

PMID:
10542408
[Indexed for MEDLINE]

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