Format

Send to

Choose Destination
J Gastroenterol. 1999 Oct;34(5):640-4.

Granulocyte-colony-stimulating-factor-producing hepatocellular carcinoma.

Author information

1
Department of Medicine III, Osaka University Medical School, Suita, Japan.

Abstract

Patients with hepatocellular carcinoma (HCC) rarely show marked granulocytosis. We report an interesting case of rapidly growing poorly differentiated HCC associated with marked granulocytosis. The blood leukocyte count decreased following several treatments for HCC, including transcatheter arterial embolization, and increased again along with tumor regrowth. The serum levels of granulocyte colony-stimulating factor (G-CSF) were markedly elevated, and immunohistochemical study showed G-CSF staining in the cytoplasm of certain HCC cells. These findings confirm that HCC in this case was a G-CSF-producing tumor.

PMID:
10535496
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center