Send to

Choose Destination
Rev Inst Med Trop Sao Paulo. 1999 May;41(3):155-8.

HIV-(1/2) indeterminate western blot results: follow-up of asymptomatic blood donors in belo horizonte, minas gerais, brazil

Author information

Fundacao Hemominas, Belo Horizonte, Minas Gerais, 30130-110, Brazil.


The clinical and public health importance of indeterminate results in HIV-(1/2) testing is still difficult to evaluate in volunteer blood donors. At Fundacao Hemominas, HIV-(1/2) ELISA is used as the screening test and, if reactive, is followed by Western blot (WB). We have evaluated 84 blood donors who had repeatedly reactive ELISA tests for HIV-(1/2), but indeterminate WB results. Sixteen of the 84 donors (19.0%) had history of sexually transmitted diseases; 18/84 (21.4%) informed receiving or paying for sex; 3/84 (3.6%) had homosexual contact; 2/26 women (7.6%) had past history of multiple illegal abortions and 3/84 (3.6%) had been previously transfused. Four out of 62 donors (6.5%) had positive anti-nuclear factor (Hep2), with titles up to 1:640. Parasitological examination of the stool revealed eggs of S. mansoni in 4/62 (6.4%) donors and other parasites in 8/62 (12.9%). Five (5.9%) of the subjects presented overt seroconversion for HIV-(1/2), 43/84 (51.2%) had negative results on the last visit, while 36/84 (42.9%) remained WB indeterminate. Although some conditions could be found associated with the HIV-(1/2) indeterminate WB results and many donors had past of risky behavior, the significance of the majority of the results remains to be determined.

Free full text

Supplemental Content

Full text links

Icon for Scientific Electronic Library Online
Loading ...
Support Center