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DNA Seq. 1998;9(3):163-9.

Computer sequence analysis of human highly conserved zinc finger modules.

Author information

1
Dept. of Biomedical Sciences and Technologies, HSR, University of Milan, Italy.

Abstract

We defined a sub-family of zinc finger proteins by computer analyses and comparisons of five new finger domains against protein databases. This subclass of the cysteine-cysteine/histidine-histidine motif shows additional well conserved amino acid patterns and belongs to the human kox and gli-Kruppel gene family, sharing also the same stretches of regulatory zinc finger-containing proteins of mouse and Xenopus. We particularly describe ZF6 cDNA which contains the most interesting sequence, encoding a putative multi-domain regulatory protein.

PMID:
10520746
DOI:
10.3109/10425179809072191
[Indexed for MEDLINE]

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