Format

Send to

Choose Destination
FEBS Lett. 1999 Sep 10;458(1):41-4.

Calcium-induced calcium release mediated by a voltage-activated cation channel in vacuolar vesicles from red beet.

Author information

1
Department of Biology, University of York, UK.

Abstract

Little is known about the mechanisms underlying calcium-induced Ca2+ release (CICR) in plants. The slow-activating vacuolar (SV) channel is both permeable to, and activated by Ca2+, and is therefore a prime candidate for a role in CICR. Cytosol-side-out vacuolar membrane vesicles loaded with 45Ca2+ showed voltage- and Ca(2+)-dependent Ca2+ release, which was sensitive to the SV channel modulators DIDS, protein phosphatase 2B and calmodulin. Significantly, voltage-dependent Ca2+ release strongly depended on cytoplasmic Ca2+ concentrations. The results support the notion that CICR occurs in plant cells and that the process can be catalysed by the SV channel on the vacuolar membrane.

PMID:
10518930
DOI:
10.1016/s0014-5793(99)01109-6
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center