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Obstet Gynecol. 1999 Oct;94(4):595-9.

Thrombotic risk during pregnancy: a population study.

Author information

1
Department of Obstetrics and Gynecology, and Coagulation Research, University of Lund, University Hospital, Sweden. pelle.lindqvist@obst.mas.lu.se

Abstract

OBJECTIVE:

To determine the incidence of pregnancy-related venous thromboembolic events and the relationship to selected risk factors such as maternal age, parity, smoking, preeclampsia, or cesarean delivery.

METHODS:

All Swedish women reported as having pregnancy-related venous thromboembolic events during 1990-1993 (608 of 479,422 deliveries) were compared with all thrombosis-free Swedish pregnant women during 1993 (114,940).

RESULTS:

The incidence of pregnancy-related venous thromboembolic events was 13 per 10,000 deliveries. Cesarean delivery was associated with a fivefold increased risk of venous thromboembolic events. Advanced age was not a significant risk factor itself, but was associated with an age-related increase in frequency of cesareans. Women with preeclampsia were at a threefold higher risk postpartum, but at no increased risk before delivery. There was a tobacco consumption-dependent increase in the risk of thrombosis among smokers.

CONCLUSION:

The incidence of pregnancy-related thrombosis was 13 per 10,000 and provided new insights to important risk factors such as age, cesarean delivery, smoking, and preeclampsia.

PMID:
10511366
DOI:
10.1016/s0029-7844(99)00308-7
[Indexed for MEDLINE]

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