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Curr Opin Plant Biol. 1999 Oct;2(5):352-8.

The ethylene-response pathway: signal perception to gene regulation.

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Department of Cell Biology and Molecular Genetics, Maryland Agricultural Experiment Station, HJ Patterson Hall, University of Maryland, College Park, MD 20742, USA.


Tremendous strides have been made in the past year toward elucidating the ethylene-response pathway. Ethylene is perceived by a family of histidine kinase-like receptors, which negatively regulate ethylene responses. Binding of ethylene requires a copper cofactor, and proper receptor function relies on a copper transporter. Downstream, EIN2 is a structurally novel protein containing an integral membrane domain. In the nucleus, the EIN3 family of DNA-binding proteins regulates transcription in response to ethylene, and an immediate target of EIN3 is a DNA-binding protein of the AP2/EREBP family.

[Indexed for MEDLINE]

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