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Arch Pathol Lab Med. 1999 Oct;123(10):957-9.

Focus of signet ring cell carcinoma in an adenoma of the sigmoid colon.

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  • 1Department of Medicine, Boston Medical Center, Boston, Mass, USA.


A case of a pedunculated adenomatous polyp of the sigmoid colon was found to have a primary focus of signet ring cell carcinoma. Histologic examination of the medium-sized polyp was consistent with an adenoma to carcinoma sequence for signet ring cell carcinoma of the colon, similar to that for the common adenocarcinomas.

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