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Mech Dev. 1999 Jun;84(1-2):153-6.

Expression pattern of macrophage migration inhibitory factor during embryogenesis.

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Functional Genomics Unit, Gene Targeting Facility, Bethesda, MD 20892, USA.


Although macrophage migration inhibitory factor (MIF) was originally identified as a lymphokine that inhibits the migration of macrophages, its ubiquitous expression suggests it may have a role beyond the immune system. Here we report a detailed characterization of MIF expression during mouse embryogenesis. The MIF expression pattern was found to parallel tissues specification and organogenesis.

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