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Br J Cancer. 1999 Aug;80(12):1979-81.

Absence of mutations in the ATM gene in forty-seven cases of sporadic breast cancer.

Author information

1
Centre for Environmental Health, Department of Biology, University of Victoria, Canada.

Abstract

Epidemiological evidence points to an increased risk of breast cancer in ataxia telangiectasia (AT) heterozygote women. Previous attempts to screen early onset or familial breast cancer patients failed to confirm an association. The issue of AT and late onset sporadic breast cancer remained unresolved. We screened 47 women who developed later onset, sporadic breast cancer for ataxia telangiectasia mutated (ATM) mutations. No mutations were found.

PMID:
10471049
PMCID:
PMC2363154
DOI:
10.1038/sj.bjc.6690630
[Indexed for MEDLINE]
Free PMC Article

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